Helen Claire Frost was born in Reigate, England, on October 17, 1952, to Dennis and Daphne Frost. Her family moved to Nanaimo, British Columbia, in 1956, where her father worked as a sweeper operator for the city. Frost moved to Prince George in 1969, and her older sister Sandy joined her that November; the two shared an apartment on the 1600 block of Queensway with a woman named Darlene and Darlene's infant child.
In the spring of 1970, Frost stayed at a home for unwed mothers in Kamloops, where she gave birth to a daughter, Sandra Jeanette, on May 13, 1970. The child was taken into government custody shortly after, and Frost's attempt to regain custody that summer was unsuccessful. Around this period, her relationship with the child's father, identified as Stefan Grumpner, ended. Frost worked odd jobs in Prince George, including as a busser at a Hudson's Bay Company cafeteria and as a gas station painter for a company operating between Prince George and Prince Rupert.
On the evening of Tuesday, October 13, 1970 — four days before her 18th birthday — Frost was at the Queensway apartment when her sister Sandy returned home around 8:00 p.m. Frost asked Sandy to go for a walk with her; Sandy declined due to the cold. Frost said she would walk alone, left around 8:20 p.m., and never returned. She was not immediately reported missing because Sandy believed she might be at a friend's house. When Frost did not return by October 15, 1970, Sandy reported her disappearance to the Royal Canadian Mounted Police (RCMP).
The RCMP took a missing person's report, but Sandy said she got the impression little was done at the time. A tip surfaced that Frost had been seen hitchhiking from a Husky gas station in Prince George, reportedly by a truck driver; the RCMP investigated but could not substantiate the tip. The case remains active, with officers assigned to it periodically since 1970 and most recently in 2017 (file 1970-70118), as Canada has no statute of limitations on serious crimes.
Sandy has led search and awareness efforts, including missing person posters, news coverage, and a dedicated Facebook page. She unsuccessfully petitioned the RCMP to add her sister to the E-Pana list of missing and murdered women connected to the Highway of Tears, as the case reportedly did not meet listing criteria. Frost is described as the first woman to have gone missing along that corridor, chronologically preceding other cases from the 1970s.
Three theories about her disappearance have circulated: accident, running away, or suicide. No public evidence supports an accident, no remains have been found, and Sandy has stated there was no suicide note or other evidence indicating Frost took her own life. Frost left behind money, clothing, and identification at the apartment, which her sister has cited as evidence against a voluntary departure. In 2018, Frost's daughter, using the name Michele Johnston, located and was reunited with Sandy after searching for her birth mother.