Murder of William McGuire (the "Suitcase Murder")

William T. "Bill" McGuire, a computer programmer and U.S. Navy veteran, was killed on April 28, 2004, the day he and his wife, nurse Melanie McGuire, closed on a new home in Warren County, New Jersey. According to prosecutors, Melanie McGuire drugged her husband, shot him with a .38 caliber revolver, and dismembered his body, placing the remains into a three-piece Kenneth Cole suitcase set.

Between May 5 and May 16, 2004, the three suitcases were recovered separately from the Chesapeake Bay area near the Chesapeake Bay Bridge–Tunnel and Fisherman Island National Wildlife Refuge. The first suitcase contained legs; the second, larger suitcase contained a head with one bullet wound and a torso with two bullet wounds; the third contained arms. A police facial reconstruction sketch was recognized by an acquaintance of Bill McGuire's, leading investigators to identify the victim and turn the investigation over to the New Jersey State Police.

Investigators developed a body of circumstantial evidence against Melanie McGuire. She had purchased a .38 caliber handgun and wadcutter cartridges from a Pennsylvania store two days before the killing. Bill McGuire's car was found abandoned at an Atlantic City motel, and surveillance footage—though too blurry to identify a driver—showed it being moved on April 30, 2004; McGuire said she had moved it as a "prank." She had applied for a protection-from-abuse order days before the killing, alleging her husband had slapped her. Investigators also learned she had been having an affair with a co-worker, Bradley Miller, and that her E-ZPass tag was recorded at a Delaware toll booth two days after the murder, a charge she later tried to have removed from her account. Forensic examiners linked plastic bags found with the body to bags Melanie had given a friend containing Bill's clothes, and matched a medical-grade towel found with the remains to towels stocked at the clinic where she worked. Green polyester fibers on a bullet were consistent with a couch cushion the couple owned, which investigators theorized was used to muffle gunshots.

Melanie McGuire was arrested on June 2, 2005, and later faced additional indictments, including hindering-apprehension charges over letters allegedly sent to police. Her trial began March 5, 2007, in Middlesex County, New Jersey. On April 23, 2007, a jury convicted her of first-degree murder, perjury, desecration of human remains, and unlawful possession of a weapon, while acquitting her of hindering-prosecution and evidence-tampering charges. A post-trial bid for a new trial, based on a jailhouse informant's claim that Bill McGuire had been killed by organized-crime figures over gambling debts, was withdrawn after the informant was found to have fabricated the story and later accused McGuire's attorney of suborning perjury. McGuire was sentenced to life in prison on July 19, 2007, and is not eligible for parole until she is 101. Her conviction was affirmed on appeal in 2011, and the New Jersey Supreme Court declined further review that same year. A 2014 motion for post-conviction relief alleging ineffective counsel was denied.