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Murder of Michael Brandon Cochran

Natalie Cochran, a Raleigh County, West Virginia pharmacist, was convicted of first-degree murder for poisoning her husband, Michael Brandon Cochran, with insulin in February 2019, and separately convicted of running a $2.5 million Ponzi scheme.

Illustrative

Michael Brandon Cochran died on February 11, 2019, six days after his wife, Natalie Paige Cochran, allegedly injected him with nonprescribed insulin at their home in Raleigh County, West Virginia. According to prosecutors, Michael had grown suspicious of the couple's contracting business and planned to travel to Virginia to investigate their dealings further. On February 5, 2019, Natalie Cochran canceled his flight and injected him with insulin. As his condition deteriorated, she reportedly told friends he would "sleep it off" and refused to take him to a hospital. He died days later.

Separately from the murder case, Natalie Cochran, a pharmacist by training, operated a Ponzi scheme from 2017 to 2019 under the guise of a government contracting business. She persuaded at least 11 individuals to invest in two companies she controlled, Technology Management Solutions and Tactical Solutions Group, falsely claiming she held lucrative government contracts. Rather than investing the funds as promised, she used investor money for personal expenses, including real estate, jewelry, and a 1965 Shelby Cobra, and used later investors' funds to pay partial returns to earlier investors. One investor alone lost more than $500,000. The scheme totaled approximately $2.5 million in losses. Cochran pleaded guilty to wire fraud and money laundering on September 21, 2020, and was sentenced to 135 months in federal prison, along with an order to pay $2.5 million in restitution and forfeit assets obtained through the scheme.

In the state murder case, prosecutors argued that Cochran killed her husband to prevent him from uncovering her fraudulent activities. Forensic experts testified at trial that Michael's death was caused by nonprescribed insulin. The jury deliberated for less than two hours before returning a guilty verdict on the first-degree murder charge. Judge H.L. Kirkpatrick, who had earlier announced he would not seek re-election, presided over the trial by special appointment. In January 2025, Cochran was sentenced to life imprisonment without the possibility of parole, with the jury recommending no mercy.

The case prompted a legislative response in West Virginia. In February 2025, state lawmakers introduced House Bill 2789, known as the Michael Brandon Cochran Act, which would mandate that intensive care units conduct C-peptide insulin tests for unconscious patients or those presenting with hypoglycemia and blood glucose levels below 49 mg/dl, aiming to help detect similar cases of insulin misuse in the future.

The case received extensive national media coverage, including a feature on the ABC News program 20/20: Small Town Big Con, as well as coverage from CBS News, Dateline NBC, Court TV, and People magazine.

Start hereVIDEOThe Case Against Natalie Cochran | Vinnie Politan InvestigatesYOUTUBE

Key facts

Victims
Michael Brandon Cochran
Date
2019
Location
Raleigh County, West Virginia
Case status
solved

Case timeline

  1. 2019-02-05

    Natalie Cochran canceled her husband's flight to Virginia, where he intended to investigate their business dealings, and allegedly injected him with insulin.

  2. 2019-02-11

    Michael Brandon Cochran died.

  3. 2020-09-21

    Natalie Cochran pleaded guilty to wire fraud and money laundering related to a Ponzi scheme.

  4. 2023-11

    Judge H.L. Kirkpatrick announced he would not run for re-election but would preside over the Cochran murder trial by special appointment.

  5. 2025-01

    Natalie Cochran was sentenced to life imprisonment without parole for first-degree murder.

  6. 2025-02

    West Virginia lawmakers introduced House Bill 2789, the Michael Brandon Cochran Act, mandating C-peptide insulin testing in ICUs.

Best coverage

Titles and descriptions are the creators’ own and may not reflect current legal status; see the dossier above for sourced case facts.

VIDEO

Creator

The Case Against Natalie Cochran | Vinnie Politan Investigates

People

  • Michael Brandon Cochran

    VICTIM

    Died on February 11, 2019, after being poisoned with nonprescribed insulin; his wife was later convicted of his murder.

  • Natalie Cochran

    CONVICTED

    Convicted of first-degree murder for poisoning her husband with insulin, sentenced to life without parole in January 2025; also pleaded guilty in 2020 to wire fraud and money laundering related to a $2.5 million Ponzi scheme.

Roles reflect public records and court outcomes at the time of writing — supporting citations are on file under Sources.

Places

Common questions

What happened to the victim?
Natalie Cochran, a Raleigh County, West Virginia pharmacist, was convicted of first-degree murder for poisoning her husband, Michael Brandon Cochran, with insulin in February 2019, and separately convicted of running a $2.5 million Ponzi scheme.
Where did the murder happen?
Raleigh County, West Virginia.
Who was convicted?
Natalie Cochran (Convicted of first-degree murder for poisoning her husband with insulin, sentenced to life without parole in January 2025; also pleaded guilty in 2020 to wire fraud and money laundering related to a $2.5 million Ponzi scheme.).
What is the current status of the case?
Status: solved.

Sources

  1. ENCYCLOPEDICNatalie CochranWikipedia · 2026-07-18
  2. OFFICIAL / AGENCYRaleigh County Pharmacist Pleads Guilty to Wire Fraud and Money LaunderingUS Department of Justice · 2026-07-18
  3. OFFICIAL / AGENCYHouse Bill 2789 (The Michael Brandon Cochran Act)wvlegislature.gov · 2026-07-18

Record history

First published
JUL 18, 2026

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