The Palestine Research Center (PRC), also known as the PLO Research Center, was established in Beirut in 1965 by the Palestine Liberation Organization to collect and analyze materials on Palestinian history, culture, and politics. Based in a seven-storey building in the Hamra district of West Beirut, it was accorded diplomatic protection by the Lebanese government and grew into a major repository of Palestinian archival material, holding around 25,000 volumes and extensive microfilm and document collections by 1982.
During the 1982 Israeli invasion of Lebanon, the Center was targeted twice by car bombings, in July and August 1982, before Israeli soldiers occupied the building in September and subsequently ransacked it, removing furniture, files, and equipment. On 15 September 1982, the library and microfilm holdings were loaded onto trucks and shipped to Israel as part of a broader Israeli operation to seize documents from PLO offices across Lebanon. Israeli officials characterized the Center as an intelligence-gathering body rather than a purely academic institution, while the PLO Research Center's director maintained the material concerned historical information on Arab families and villages in pre-1948 Palestine.
On 6 February 1983 (2 p.m. local time), a car bomb containing an estimated 150 kilograms of TNT destroyed the building housing the Center. Among those killed were Hanneh Shahin, the wife of then-director Sabri Jiryis, who had stopped by shortly before the weekend closing; three people who died of smoke inhalation after being trapped in an elevator; and the building's concierge and a telephone operator. The bombing has been attributed to a car bomb placed by the Front for the Liberation of Lebanon from Foreigners, described as an Israeli proxy group. Files that researchers had gathered after the 1982 raids, stored on one floor of the building, were also destroyed in the explosion.
In the aftermath, the PLO sought the return of the seized archive as a condition of a prisoner exchange with Israel. On 24 November 1983, Israeli and Palestinian prisoners were exchanged along with material Israel described as the PLO archive, which had reportedly been copied by Israel beforehand and was then shipped via the International Red Cross to Algeria. On 19 December 1983, the UN General Assembly passed Resolution 38/180B condemning Israel for seizing and removing the archives. The whereabouts and condition of the material sent to Algeria remain uncertain. Separately, research by Israeli scholar Rona Sela indicated that some of the seized material remained in Israeli military archives in Tel Aviv as of 2008. The Center was later bombed again by Lebanese groups and eventually relocated to Nicosia, Cyprus.