In the winter of 1823–1824, a small band of Native Americans—of uncertain but possibly mixed Seneca, Shawnee, and Delaware origin—established a hunting and trapping camp along Deer Lick Creek near the falls of Fall Creek, in what is now Pendleton, Indiana. The group included two adult men known to local settlers as Logan and Ludlow, a third man called M'Doal, three women, two boys, and two girls. Tensions reportedly grew between some settlers—James Hudson, Thomas Harper, and John T. Bridge Sr.—and members of the band in the days before the attack, following disputes over trapping, trade, and a dog.
On March 22, 1824, seven white men—Harper, Hudson, John T. Bridge Sr., his sons James and John Bridge Jr., Andrew Sawyer, and Sawyer's son Stephen, along with a boy named Andrew Jones—approached the camp under the pretext of seeking help finding missing horses. Logan and Ludlow agreed to help track the horses and were led into the woods, where they were shot and killed. The remaining assailants then returned to the camp and killed the three women and four children. M'Doal, who was not present when the attackers arrived, escaped and was never found. One injured woman survived for a short time before dying.
Authorities arrested most of the men within a week; Harper fled and was never captured. The four men charged—James Hudson, Andrew Sawyer, John T. Bridge Sr., and John Bridge Jr.—were tried in Madison County. Hudson was tried and convicted first, in October 1824, and was hanged on January 12, 1825. The Indiana Supreme Court upheld his conviction on appeal. The remaining three men were tried in May 1825; Sawyer was convicted of manslaughter for one victim and murder on retrial for other counts, while Bridge Sr. and Bridge Jr. were convicted of murder. Sawyer and Bridge Sr. were hanged on June 3, 1825. Moments before his scheduled execution, Governor James B. Ray pardoned the eighteen-year-old Bridge Jr., citing his youth, remorse, and the influence of others, particularly his father.
The prosecutions were widely reported and are described as the first instance under U.S. law in which white men were convicted, sentenced to death, and executed for killing Native Americans. Despite this, the case did not establish a lasting precedent for equal justice, and further violence and displacement of Native peoples in the region continued in subsequent decades. Records of the case are incomplete; original trial transcripts were destroyed in an 1880 courthouse fire, and no testimony or accounts from surviving Native Americans were recorded. The site is commemorated by a stone marker in Pendleton's Fall Creek Park and a state historical marker near Markleville, Indiana. The events later inspired Jessamyn West's 1975 novel, The Massacre at Fall Creek.