Reuben Eli Ladd was born in 1869 and grew up near Mooreland, in Henry County, Indiana. His parents were Isaac and Sarah Ladd (née Means), and he lived with them and his younger sister, Julia, on the farm of his maternal grandparents, Reuben and Leah Means, in Blue River Township. The Means family had lived in the area since at least 1840. Ladd worked on the family farm from a young age and was also employed as a barber, and some contemporary newspapers referred to him as the "Mooreland barber."
On February 7, 1890, in Blountsville, Indiana, Ladd was chased and shot by a small group of white men who fired more than fifty rounds at him. The Muncie Morning News reported on February 8, 1890, that Ladd had been shot six times. Ladd was lynched after confronting a vigilante group of white men who accused him of assaulting a white woman. The lynching has been described as part of a broader pattern in which white mobs in Indiana used violence to enforce Jim Crow-era racial control during the Reconstruction period. Men frequently cited as leaders of the mob include William Rozell (also spelled Razell), Cassius (sometimes Charles) Lake, Charles Smelzer, John Davis, and J.P. Smith. Some accounts suggest there may have been an ongoing "private feud" between Ladd and one of these men.
On February 10, 1890, arrest warrants were issued for William Rozell, Cassius Lake, Charles Smeltzer, and J.P. Smith, who were taken to the Henry County jail to await trial. On February 15, 1890, the Muncie Morning News reported that attorney Rollin Warner had been engaged to defend the accused men. On May 22, 1890, a jury acquitted Cassius Lake. On June 23, 1890, the "Smeltzer-Ladd" murder trial began before Judge Lotz in Delaware County Court. The Muncie Morning News reported on July 7, 1890, that Smeltzer had been convicted of manslaughter and sentenced to two years in the Indiana State Prison.
A separate trial for William Rozell began on December 29, 1890, at the New Castle Circuit Court. On January 11, 1891, John P. Smith testified that Rozell had conspired to murder Ladd the night before the lynching. Rozell was subsequently convicted of manslaughter and sentenced to two years in prison. Smith pleaded guilty to manslaughter and also received a two-year sentence.
The case drew regional attention; the Wheeling Register, a West Virginia newspaper, reportedly commented critically on what it characterized as "Hoosier hypocrisy," noting that the lynching had occurred in a county that voted Republican.